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磷酸甲羥戊酸激酶抗體

產(chǎn)品貨號(hào)：

BN41084R
中文名稱：

磷酸甲羥戊酸激酶抗體
英文名稱：

Rabbit anti-PMVK Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN41084R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN41084R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	PMVK
中文名稱	磷酸甲羥戊酸激酶抗體
別名	hPMK; HUMPMKI; Phosphomevalonate kinase; PMK; PMK PEN; PMKA; PMKase; PMKI; PMKPEN; PMVK; PMVK_HUMAN; EC 2.7.4.2.
研究領(lǐng)域	腫瘤細(xì)胞生物免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來(lái)源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, (predicted: Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	22kDa
細(xì)胞定位	細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated Synthesised phosphopeptide derived from human PMVK:15-120/192
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Subunit: Monomer (By similarity). Subcellular Location: Peroxisome. Tissue Specificity: Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. SWISS: Q15126 Gene ID: 10654 Database links: Entrez Gene: 10654 Human Entrez Gene: 68603 Mouse Entrez Gene: 310645 Rat Omim: 607622 Human SwissProt: Q15126 Human SwissProt: Q9D1G2 Mouse SwissProt: Q5RK24 Rat Unigene: 30954 Human Unigene: 34242 Mouse Unigene: 22202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.